C1333991[trait identifier] AND "KCCC/NGS Laboratory, Kuwait Cancer Con - ClinVar

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Items: 31

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 90140	NM_000249.4(MLH1):c.303T>G (p.Gly101=)	MLH1	Single nucleotide variant (synonymous variant +3 more)	Lynch syndrome	GLikely benign
Select item 90156	NM_000249.4(MLH1):c.307-29C>A	MLH1	Single nucleotide variant (intron variant)	Lynch syndrome	GBenign
Select item 17094	NM_000249.4(MLH1):c.350C>T (p.Thr117Met)	MLH1 (T117M +2 more)	Single nucleotide variant (missense variant +1 more)	Lynch syndrome	GPathogenic
Select item 36551	NM_000249.4(MLH1):c.381-41A>G	MLH1	Single nucleotide variant (intron variant)	Lynch syndrome	GBenign
Select item 36552	NM_000249.4(MLH1):c.453+25A>G	MLH1	Single nucleotide variant (intron variant)	Lynch syndrome	GBenign
Select item 90227	NM_000249.4(MLH1):c.453+79A>G	MLH1	Single nucleotide variant (intron variant)	Lynch syndrome	GBenign
Select item 90236	NM_000249.4(MLH1):c.454-51T>C	MLH1	Single nucleotide variant (intron variant)	Lynch syndrome	GBenign
Select item 90243	NM_000249.4(MLH1):c.474C>T (p.Asn158=)	MLH1	Single nucleotide variant (synonymous variant +2 more)	Lynch syndrome 1	GBenign
Select item 36554	NM_000249.4(MLH1):c.545+20A>T	MLH1	Single nucleotide variant (intron variant)	not provided +5 more	GBenign
Select item 36555	NM_000249.4(MLH1):c.588+11G>C	MLH1	Single nucleotide variant (intron variant)	Lynch syndrome 1	GBenign
Select item 371941	NM_000249.4(MLH1):c.589-25G>A	MLH1	Single nucleotide variant (intron variant)	Colorectal cancer, hereditary nonpolyposis, type 2	GLikely benign
Select item 36556	NM_000249.4(MLH1):c.589-15C>T	MLH1	Single nucleotide variant (intron variant)	Lynch syndrome	GLikely benign
Select item 41640	NM_000249.4(MLH1):c.637G>A (p.Val213Met)	MLH1 (V213M +2 more)	Single nucleotide variant (missense variant +1 more)	Lynch syndrome	GBenign
Select item 36557	NM_000249.4(MLH1):c.655A>G (p.Ile219Val)	MLH1 (I219V +2 more)	Single nucleotide variant (missense variant +1 more)	Lynch syndrome	GBenign
Select item 183730	NM_000249.4(MLH1):c.954C>T (p.His318=)	MLH1	Single nucleotide variant (synonymous variant +2 more)	not specified +4 more	GBenign/Likely benign
Select item 42496	NM_000249.4(MLH1):c.977T>C (p.Val326Ala)	MLH1 (V326A +3 more)	Single nucleotide variant (missense variant +2 more)	Lynch syndrome	GBenign
Select item 2573180	NM_000249.4(MLH1):c.1036C>T (p.Gln346Ter)	MLH1 (Q105* +4 more)	Single nucleotide variant (nonsense +1 more)	Colorectal cancer, hereditary nonpolyposis, type 2	GPathogenic
Select item 89614	NM_000249.4(MLH1):c.1038+51C>T	MLH1	Single nucleotide variant (intron variant)	Lynch syndrome 1	GLikely benign
Select item 41632	NM_000249.4(MLH1):c.1151T>A (p.Val384Asp)	MLH1 (V384D +5 more)	Single nucleotide variant (missense variant)	Lynch syndrome	GBenign
Select item 41634	NM_000249.4(MLH1):c.1217G>A (p.Ser406Asn)	MLH1 (S406N +5 more)	Single nucleotide variant (missense variant)	Lynch syndrome	GBenign
Select item 89722	NM_000249.4(MLH1):c.1410-54C>T	MLH1	Single nucleotide variant (intron variant)	Lynch syndrome	GBenign
Select item 237312	NM_000249.4(MLH1):c.1410-10T>G	MLH1	Single nucleotide variant (intron variant)	Hereditary nonpolyposis colorectal neoplasms +6 more	GBenign/Likely benign
Select item 89752	NM_000249.4(MLH1):c.1489del (p.Arg497fs)	MLH1 (R156fs +5 more)	Deletion (frameshift variant)	Lynch syndrome	GPathogenic
Select item 36541	NM_000249.4(MLH1):c.1558+14G>A	MLH1	Single nucleotide variant (intron variant)	Lynch syndrome	GBenign
Select item 36542	NM_000249.4(MLH1):c.1668-19A>G	MLH1	Single nucleotide variant (intron variant)	Lynch syndrome	GBenign
Select item 41636	NM_000249.4(MLH1):c.1808C>G (p.Pro603Arg)	MLH1 (P603R +5 more)	Single nucleotide variant (missense variant +1 more)	Lynch syndrome	GLikely benign
Select item 17089	NM_000249.4(MLH1):c.1852_1853delinsGC (p.Lys618Ala)	MLH1 (K618A +5 more)	Indel (missense variant +1 more)	Lynch syndrome	GBenign
Select item 41637	NM_000249.4(MLH1):c.1963A>G (p.Ile655Val)	MLH1 (I655V +6 more)	Single nucleotide variant (missense variant +1 more)	Lynch syndrome	GLikely benign
Select item 962013	NM_000249.4(MLH1):c.2087C>A (p.Thr696Asn)	MLH1 (T641N +7 more)	Single nucleotide variant (missense variant +1 more)	Colorectal cancer, hereditary nonpolyposis, type 2 +1 more	GUncertain significance
Select item 90042	NM_000249.4(MLH1):c.2101C>A (p.Gln701Lys)	MLH1 (Q701K +7 more)	Single nucleotide variant (missense variant +1 more)	Lynch syndrome	GLikely benign
Select item 36547	NM_000249.4(MLH1):c.2152C>T (p.His718Tyr)	MLH1 (H718Y +8 more)	Single nucleotide variant (missense variant)	Lynch syndrome	GBenign

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Items: 31